At the San Diego Center for Restorative Medicine, Dr. Jonathan Kalman specializes in treating chronic pain and sports injuries with Prolotherapy. Prolotherapy is an injection technique performed at the site of injured tissue that activates fibroblasts in the body to synthesize collagen and reinforce connective tissue.  Exposure of fibroblasts to growth factors (either naturally occurring or added) has been proven to cause new cell growth and collagen deposition.  PRP/Prolotherapy raises the level of growth factors to initiate or resume connective tissue repair sequence which had prematurely aborted or never started.  Animal biopsy studies show ligament thickening, enlargement of the tendinosseous junction, and strengthening of the tendon or ligament after Prolotherapy injections.

Dextrose PRP/Prolotherapy

Dextrose PRP/Prolotherapy is the original form of PRP/Prolotherapy originating in the 1930’s. Concentrated dextrose or other natural substances, are used as an irritant to stimulate a mild inflammation which prompts the body into thinking the area is injured and to begin healing again. Dextrose PRP/Prolotherapy raises growth factor levels or effectiveness to promote tissue repair, reducing or eliminating musculoskeletal pain. Dextrose PRP/Prolotherapy is practiced by physicians in the U.S. and worldwide, has been shown effective in treating many musculoskeletal conditions. It is commonly referred to as simply “PRP/Prolotherapy”.